There's no comparison to fresh squeezed for sure. My secret was a splash of OJ, and a splash of pineapple juice. The sweet of the pineapple takes the edge of the citric acid in the lime and OJ.When I used to drink, I LOVED a wicked PROPER ‘Rita, but also had the bullshiit guts affliction.. I found that for ME, when I booted the trash sour mix, and began doing them with fresh squeezed lime, agave nectar, and a SPLASH of OG Sunny D; I never had another issue.. They tasted PHENOMENALLY better as well! Absolutely no comparison. But like I said-that’s my own experience, and your results may vary.